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Agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, neutropenia, hemolytic anemia, megaloblastic anemia, hypoprothrombinemia, methemoglobinemia, eosinophilia. There were no abnormalities in the 10 children whose mothers received the drug during the first trimester.
Serum digoxin levels should be monitored. Hematological changes indicative of folic acid deficiency may occur in elderly patients.
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Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. Use this medication for the full prescribed length of time.
Caution should be exercised when BACTRIM is administered to a nursing woman, especially when breastfeeding, jaundiced, ill, stressed, or premature infants because of the rosuvastatin benefits risk of bilirubin displacement and kernicterus. They do not treat viral infections e.
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Close monitoring of serum potassium is warranted in these patients. Severe cases of thrombocytopenia that are fatal or life threatening have been reported.
Your symptoms may improve before the infection is completely cleared. During treatment, adequate fluid intake and urinary output should be ensured to prevent crystalluria. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect.
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Avoid exposure to sunlight or tanning beds. Tell any doctor who treats you that you are using Bactrim. Arthralgia and myalgia.
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Take Bactrim exactly as prescribed by your doctor. Porphyria and Hypothyroidism As with all drugs containing sulfonamides, caution is advisable in patients with porphyria or thyroid dysfunction.
BACTRIM, specifically the trimethoprim component, can interfere with a serum methotrexate assay as determined by the competitive binding protein technique CBPA when a bacterial dihydrofolate reductase is used as the binding protein.
Call your doctor for medical advice about side effects. Geriatric Pharmacokinetics.
Pyrexia, hematuria and crystalluria may be noted. In an established infection, they will not eradicate the streptococcus and, therefore, will not prevent sequelae such as rheumatic fever. Traveler's Diarrhea in Adults: Tell your doctor if you are breast-feeding a baby.
Nonteratogenic Effects: This medication can cause unusual results with certain medical tests. Allergic Reactions:
This medication can make you sunburn more easily. Porphyria and Hypothyroidism As with all drugs containing sulfonamides, caution is advisable in patients with porphyria or thyroid dysfunction. If signs of bone marrow depression occur, the patient should be given leucovorin 5 to 15 mg daily until normal hematopoiesis is restored.
These studies are further limited by recall, selection, and information biases, and by limited generalizability of their findings. Bupropion prescribing information Abnormalities High dosage of trimethoprim, as used in patients with P. Signs of acute overdosage with trimethoprim include nausea, vomiting, dizziness, headache, mental depression, confusion and bone marrow depression.
Other drugs may interact with sulfamethoxazole and trimethoprimincluding prescription and over-the-counter medicines, vitamins, and herbal products.
In mice following oral administration of trimethoprim, no DNA damage in Comet assays of liver, kidney, lung, spleen, or bone marrow was recorded. Close monitoring of serum potassium is warranted in these patients. Lastly, outcome measures varied between studies, limiting cross-study comparisons. Pharmacokinetics parameters for sulfamethoxazole were similar for geriatric subjects and younger adult subjects.
Carcinogenesis, Mutagenesis, Impairment of Fertility: CDAD must be considered in all patients who present with diarrhea following antibiotic use. Caution should be exercised when BACTRIM is administered to a nursing woman, especially when breastfeeding, jaundiced, ill, stressed, or premature infants because of the potential risk of bilirubin displacement and kernicterus.
Clostridium difficile associated diarrhea Clostridium difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including BACTRIM, and may range in severity from mild diarrhea to fatal colitis.
Follow all directions on your prescription label. Agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, neutropenia, hemolytic anemia, megaloblastic anemia, hypoprothrombinemia, methemoglobinemia, eosinophilia.
Other drugs may interact with sulfamethoxazole and trimethoprimincluding prescription and over-the-counter medicines, vitamins, and herbal products. Bactrim will not treat a viral infection such as the common cold or flu.
Sulfonamides can also displace methotrexate from plasma protein binding sites and can compete with the renal transport of methotrexate, thus increasing free methotrexate concentrations. Acute Exacerbations of Chronic Bronchitis in Adults:
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Follow all directions on your prescription label. Seek emergency medical attention or call the Poison Help line at Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation.
Related questions. Use this medication for the full prescribed length of time. Shake the oral Bactrim suspension liquid well just before you measure a dose. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors.
Not all possible interactions are listed in this medication guide. Renal failure, interstitial nephritis, BUN and serum creatinine elevation, toxic nephrosis with oliguria and anuria, crystalluria and nephrotoxicity in association with cyclosporine. Other drugs may interact with sulfamethoxazole and trimethoprimincluding prescription and over-the-counter medicines, vitamins, and herbal products.
Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. Pediatric Use: Do not use anti-diarrhea medicine unless your doctor tells you to.
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The trimethoprim component of BACTRIM may cause hyperkalemia when administered to patients with underlying disorders of potassium metabolism, with renal insufficiency or when given concomitantly with drugs known to induce hyperkalemia, such as angiotensin converting enzyme inhibitors.
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They do not treat viral infections e. In some rabbit studies, an overall increase in fetal loss dead and resorbed conceptuses was associated with doses of trimethoprim 6 times the human therapeutic dose based on body surface area. For the treatment of acute otitis media in pediatric patients due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae when in the judgment of the physician sulfamethoxazole and trimethoprim offers some advantage over the use of other antimicrobial agents.
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For the treatment of documented Pneumocystis jiroveci pneumonia and for prophylaxis against P.
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Allergic Reactions: If a significant blood dyscrasia or jaundice occurs, specific therapy should be instituted for these complications or sulfamethoxazole / trimethoprim. Pediatric Use:, bactrim ds generic.
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For the treatment of documented Pneumocystis jiroveci pneumonia and for prophylaxis against P. Close monitoring of serum potassium is warranted in these patients. Bactrim drug interactions in more detail Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Bactrim only for the indication prescribed.
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