Teva's generic of Imitrex® Injection: Sumatriptan Injection, USP (autoinjector)Add imitrex to basket
Imitrex (sumatriptan, sumatriptan) 100 mg, is prescription medicine used to treat erectile dysfunction (ed).
Imitrex be sure to tell your doctor about all of the medications you take and any other medical conditions as your dose may need to be adjusted. In the presence of sexual stimulation.
|Trade names||Imitrex, Imigran,Treximet|
|License data||US FDA: Sumatriptan|
|Routes of administration||tablet, subcutaneous injection, nasal spray, transdermal electrophoresis|
|ATC code||N02CC01 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Bioavailability||15% (oral)/ 96% (s.c)|
|Elimination half-life||2.5 hours|
|Excretion||60% urine; 40% feces|
Do not use any other type of syringe because you may not get the right amount of medication. Do not inject sumatriptan through clothing.
It should also be noted that patients with migraine source webpage be at increased risk of certain cerebrovascular events e. The systematic approach described above is intended to reduce the likelihood that patients with unrecognized cardiovascular disease will be inadvertently exposed to sumatriptan.
Basilar or hemiplegic migraine. Other data suggest that treatment with sumatriptan is not associated with an increase in early recurrence of headache and has little effect on the incidence of latter-occurring headaches i.
Neither of these adverse events was associated with a serious clinical outcome. Oral administration of sumatriptan to rats prior to and throughout gestation resulted in embryofetal toxicity decreased body weight, decreased ossification, increased incidence of skeletal abnormalities.
The studies did not mentax generic name the efficacy of sumatriptan nasal spray compared with placebo in the treatment of migraine in adolescents.
Monitor cardiovascular function in long-term intermittent use.
IMITREX Injection (sumatriptan succinate) -GSKSource
There is no evidence that concomitant use of migraine prophylactic medications has any effect on the efficacy of sumatriptan. If concomitant treatment with sumatriptan and an SSRI e. Withdrawal of the treatment may be necessary.
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac sovaldi hepatitis c price and of concomitant disease or other drug therapy. Oral administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in increased incidences of embryolethality and fetal cervicothoracic vascular and skeletal abnormalities.
The highest oral and intravenous no-effect doses for developmental toxicity in rabbits were 15 and 0. Overdoses would be expected from animal data dogs at 0.
In offspring of pregnant rats treated orally with sumatriptan during organogenesis, there was a decrease imitrex pen pup survival. Latex allergy Inj. Patients should be directed to use flagyl online sites with an adequate skin and subcutaneous thickness to accommodate the length of the needle.
In 2 cytogenetics assays the in vitro human lymphocyte assay and the in vivo rat micronucleus assay sumatriptan was not associated with imitrex pen activity.imitrex alternative name:
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In the U. Nursing mothers avoid nursing for 12 hours after treatment. In assessing this information, the following additional findings should be considered.
In a study using data from the Swedish Medical Birth Register, live births to women who reported imitrex pen triptans or ergots during pregnancy were compared with those of women who did not. The studies did not establish the efficacy of sumatriptan nasal spray compared with placebo click here the treatment of migraine in adolescents.
Several studies have suggested that women with migraine may be at increased risk of preeclampsia during pregnancy.
|Imitrex other names||cinie, triptagram, nograine, migriptan|
|Active substance||sumatriptan, sumatriptan|
|Best price||$10.26 per dose|
|Besteller||10 pills x 100 mg|
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Significant hypertensive episodes, including hypertensive crises, have been reported on rare occasions in patients with or without a history of hypertension see WARNINGS: Additional smaller observational studies evaluating use of sumatriptan during pregnancy have not suggested an increased risk of teratogenicity.
However, no effects on the retina related to treatment with sumatriptan were noted in finasteride proscar of the toxicity studies. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline.
The osmolality of both injections is mOsmol. Such reactions can be life threatening or fatal.
Sumatriptan injection is also used piroxicam structure treat the symptoms of cluster headaches severe headaches usually on one side of the head or around one eye.
Earlier examinations for these toxicities were not conducted and no-effect doses were not established; however, the relative plasma exposure at the lowest dose tested was approximately 3 times the human exposure after a 6-mg subcutaneous dose.
The pharmacokinetics of subcutaneously administered sumatriptan in patients with severe hepatic impairment has not been studied.
Geriatric Use The use of sumatriptan in elderly patients is not recommended because elderly patients are more likely to have decreased hepatic function, they imitrex pen at higher risk for CAD, and blood pressure increases may be more pronounced in the elderly see Imitrex pen Defects in the corneal epithelium were noted in a week study.
Racial Groups: It is recommended that patients who are intermittent long-term users of sumatriptan and who have or acquire risk factors predictive of CAD, as described above, undergo periodic interval cardiovascular evaluation as they continue to use sumatriptan.
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Use a different body area each time you give yourself a shot. Keep out of the reach of children.
These studies did not establish the efficacy of oral sumatriptan compared with placebo in the treatment of migraine in adolescents. On clinical grounds, the longer the latency between the administration of IMITREX and the onset of the clinical event, the less likely the association is to be causative.
Patients with Hepatic Impairment:
Similarly, patients who experience other symptoms or signs suggestive of decreased arterial flow, such as ischemic bowel syndrome or Raynaud syndrome, following sumatriptan should be evaluated for atherosclerosis or predisposition to vasospasm see WARNINGS: IMITREX should also be administered imitrex pen caution to patients with diseases that may alter the absorption, metabolism, or excretion of drugs, such as impaired hepatic or renal function.
Some of these events occurred in patients who had no findings of CAD and appear to represent consequences of coronary artery vasospasm.
In a study using imitrex pen from the Swedish Medical Birth Register, live births to women who reported using triptans or ergots during pregnancy were compared with those of women who did not. Serotonin syndrome symptoms may include mental status changes e. Of the 20 infants with reported birth defects after exposure to sumatriptan in the first trimester, 4 infants had ventricular septal defects, including one imitrex pen who was exposed to both sumatriptan and naratriptan, and 3 infants had pyloric stenosis.
- Patients should be cautioned about the risk of serotonin syndrome with the use of sumatriptan or other triptans, especially during combined use with SSRIs or SNRIs
- In developmental toxicity studies in rats and rabbits, oral administration of sumatriptan to pregnant animals was associated with embryolethality, fetal abnormalities, and pup mortality
- There have been rare reports where patients received sumatriptan for imitrex pen headaches that were subsequently shown to have been secondary to an evolving neurologic lesion see WARNINGS
- It should also be noted that patients with migraine may be at increased risk of certain cerebrovascular events e
- Do not throw away the autoinjector unit, because refills are available
Oral administration of sumatriptan imitrex pen pregnant rabbits during the period of organogenesis resulted in increased incidences of embryolethality and fetal cervicothoracic vascular and skeletal abnormalities. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline.
There are no data on the effects of sumatriptan on the breastfed infant or the effects of sumatriptan on milk production. This medicine is given as a shot under your skin usually on the stomach, thighs, or upper arms.
Clinical data to determine the frequency of serious adverse reactions in pediatric patients who might receive subcutaneous, oral, or intranasal IMITREX are not presently available, webpage. No other birth defect was reported for more than 2 infants in this group.
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Your doctor may need to change the doses of your medications or monitor you carefully for side effects. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine.
Increase in Blood Pressure. Corneal Opacities Sumatriptan causes corneal opacities and defects in the corneal epithelium in dogs; this raises the possibility that these changes may occur in humans. The systematic approach described above is intended to reduce the likelihood that patients with unrecognized cardiovascular disease will be inadvertently exposed to sumatriptan.
|IMITREX should also be administered with caution to patients with diseases that may alter the absorption||Oral treatment of pregnant rats with sumatriptan during the latter part of gestation and throughout lactation resulted in a decrease in pup survival||Concomitant Drug Use In patients taking MAO-A inhibitors|
|Latex allergy Inj||Reevaluate if no response||Therefore|
Drug-Associated Cerebrovascular Events and Fatalities Cerebral hemorrhage, subarachnoid hemorrhage, stroke, and other cerebrovascular events have atenolol and hair loss reported in patients treated with oral or subcutaneous sumatriptan, and some have resulted in fatalities.
The sensitivity of cardiac diagnostic imitrex statdose pen to detect cardiovascular disease or predisposition to coronary artery vasospasm is modest, at best. Intravenous administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in an increased incidence of embryolethality.
Oral administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in increased incidences of embryolethality and fetal cervicothoracic vascular and skeletal abnormalities.
Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline. On clinical grounds, the longer the latency between the administration of IMITREX and the onset of the clinical event, the less likely the association is to be causative.
Nursing Mothers Sumatriptan is excreted in human breast milk following subcutaneous administration. Overdoses would be expected from animal data dogs at 0.
It is strongly recommended that sumatriptan not be given to patients in whom unrecognized CAD is predicted by the presence of risk factors e. Lower doses of IMITREX injection may also prove effective, although the proportion of patients obtaining adequate relief was decreased and the latency to that relief is greater with imitrex statdose pen doses or buy sumatriptan 50mg & mg tablets online.
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Imitrex, 2 reviews:
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. Concomitant Drug Use.
2 / 5 stars
Oral administration of sumatriptan to rats prior to and throughout gestation resulted in embryofetal toxicity decreased body weight, decreased ossification, increased incidence of skeletal abnormalities.
4 / 5 stars